Predicting the Effectiveness of Beta-Blocker Therapy in Vasovagal Syncope

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Predicting the effectiveness of beta-blocker therapy in vasovagal syncope.

There has been a great deal of interest in the therapeutic role of beta-adrenergic blockade in patients suffering from vasovagal syncope. The efficacy of beta-blockers in these patients may be due to blunting of elevated catecholamine levels that precede vasovagal syncope (1). Notwithstanding the widespread use of beta-blockers in the past, some studies on chronic beta-blocker use have been les...

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Vasovagal syncope and vasovagal disease.

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Therapy of vasovagal syncope: to prevent the vasovagal reflex or to treat the impending reflex?

Vasovagal syncope (VVS) can be classical (typical) or non-classical (atypical). Classical VVS is diagnosed when precipitating events, such as emotional or orthostatic triggers, are associated with typical autonomic prodromes. If triggers and/or prodromes are not present, VVS is defined as non-classical. The mechanisms of VVS have not been completely elucidated. Our knowledge of the afferent par...

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Vasovagal syncope interrupting sleep?

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Recurrent Postural Vasovagal Syncope

Background—The pathophysiology of vasovagal syncope is poorly understood, and the treatment usually ineffective. Our clinical experience is that patients with vasovagal syncope fall into 2 groups, based on their supine systolic blood pressure, which is either normal ( 100 mm Hg) or low (70–100 mm Hg). We investigated neural circulatory control in these 2 phenotypes. Methods and Results—Sympathe...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2008

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2008.02.070